Bipolar I and Bipolar II disorder are serious, highly prevalent conditions that affect nearly six million of adults in the United States characterized by recurrent episodes of mania or hypomania interposed with episodes of major depression. The major depressive episodes in Bipolar I and Bipolar II are similar. The disorders only differ in the severity of their manic episodes.
Bipolar depression remains a significantly underserved medical need.
Bipolar depression is the most common clinical presentation of bipolar disorder. These episodes tend to last longer, recur more often and are associated with a worse prognosis than the manic/hypomanic episodes. Bipolar depression remains a significantly underserved medical need with only a few FDA-approved treatment options available.