Schizophrenia is a disabling and chronic mental illness that affects approximately 2.4 million adults in the United States. The clinical presentation of schizophrenia is diverse. Acute exacerbations are characterized by psychotic symptoms, including auditory hallucinations and delusions, often requiring hospitalization. The disease is chronic and lifelong, often accompanied by depression, and gradual deterioration of social functioning and cognitive ability.
Schizophrenia affects ~1% of adults in the United States.
Patients with schizophrenia face a major economic burden. Residual symptoms can contribute to social and employment issues and only a third of patients are able to work.
Drug related adverse events, such as weight gain and movement disorders, are often associated with discontinuation of treatment.